Dialogue
In this population of patients with T2D at the preinsulin stage, most of the modifiable cardiovascular risk factors we investigated showed deviations from recommended goals (see Figure 1 for goals). As BMI strata increased, we found that impairment of most cardiovascular risk factors increased as well, and this was confirmed using generalized logit analysis. Indeed, cardiovascular risk factors were most prominent in patients in the higher BMI strata. This finding is in agreement with that of Gomis et al. , who reported an increased frequency of dyslipidemia and hypertension with increasing BMI among 7371 Spanish patients with T2D (P < .0001). By contrast, although glycemic control (HbA1c strata) also appeared to be associated with most of the cardiovascular risk factors we considered, the association was significant only for duration of T2D and dyslipidemia.
This character create entail a reduction in age start away from T2D
Significant, Body mass index strata was basically plus inversely associated with age and you may lifetime of T2D. Prior epidemiological degree from inside the Spain, did along the whole age spectrum of all round population, had located an immediate connection anywhere envie site de rendez-vous between Bmi and you may many years to the latest 5th or 6th years [25, 26]. Our very own clients, each of just who got T2D, had large Bmi viewpoints normally than their Spanish inhabitants colleagues [25, 27, 28]. The fresh inverse relationship anywhere between Bmi strata and you can years in the present investigation get get in touch with the approved role one to carrying excess fat at very early many years enjoys in the modern T2D crisis [29–31].
At exactly the same time, the newest prices out-of T2D frequency within the Spain was indeed considerably large and you may integrated the great majority regarding undiagnosed cases, which have been more youthful and a lot more obese than ever before identified clients . (more…)